A New Study Points to MDMA as a Powerful Treatment for PTSD

May 12, 2021 0 Comments

Post-Traumatic Stress Disorder (PTSD), will affect some 26 million Americans at some point in their lives, according to the Department of Veterans Affairs. The condition, characterized by depression, hopelessness, memory problems, difficulty maintaining relationships, and recurrent visions of the trauma-causing event is notoriously hard to treat. Up to a third of people with the condition are still symptomatic 10 years after diagnosis, and the main therapeutic drugs of choice—the selective serotonin reuptake inhibitors sertraline and paroxetine—fail in up to 60% of patients. A study published yesterday, however, suggests that there may be a powerful new medication to battle the condition: MDMA, the primary chemical in the drugs colloquially known as ecstasy and molly.

In a Phase 3 trial led by neurologist Jennifer Mitchell of the University of California, San Francisco, treatment with three doses of MDMA—accompanied by one-on-one therapy—over the course of 18 weeks was significantly more effective in treating … Read the rest

Expert Q&A: MAPS and Psychedelic-Assisted Psychotherapy

May 12, 2021 0 Comments

After decades of limited research and legal roadblocks to medical and recreational use, psychedelic drugs are rapidly remerging as treatments of interest in psychiatry. Cannabis for medical use is widely available across the United States, and in the 2020 elections, a number of states relaxed drug laws, with Oregon allowing psychedelic treatments at medical centers.1

These legal changes, particularly regarding nonmedical or recreational use, will have many physicians worried about the development of substance use disorders in broad swathes of the population. However, relaxed regulations may offer an opportunity to learn more about how the diverse range of psychedelic drugs can be applied as treatments in psychiatric settings.2-4

The first part of this series of articles (Psychedelic Drugs: Lessons From Ketamine and Psilocybin) explored a couple of very different psychedelic treatments for psychiatric disorders, namely esketamine and psilocybin-based treatments for major depressive disorder (MDD).5 Whereas the development … Read the rest

Health Risks From Plastic Water Pipes

May 11, 2021 0 Comments

Everyone knows that neither group is experiencing optimum situations for longevity. Along with Dr. Marie Nyswander and Dr. Kreek, Dole pioneered methadone therapy for heroin addicts.

jaguar health news 2021

The International Health Briefing Book is a resource for effectively-informed resolution-making on issues involving U.S. engagement in global well being. In 1986, the WHO, within the Ottawa Constitution for Health Promotion, said that well being is “a resource for on a regular basis life, not the objective of dwelling. Well being is a constructive idea emphasizing social and private assets, in addition to bodily capacities.” Classification systems such because the WHO Household of Worldwide Classifications (WHO-FIC), which consists canadian pharmacy of the Worldwide Classification of Functioning, Disability, and Well being (ICF) and the Worldwide Classification of Diseases (ICD) also outline health. The report reveals health care prices are additionally a leading contributor to health inequities. For instance, 6{d88ec4a771b38d36e747acb18ed3240a91adf6c3faa273fad2adf67e1f235525} of adults … Read the rest

Teens Aged 12 to 15 Can Now Get Pfizer-BioNTech COVID-19 Vaccine in the U.S.

May 11, 2021 0 Comments

On May 10, the U.S. Food and Drug Administration (FDA) extended authorization of the Pfizer-BioNTech COVID-19 vaccine to 12- to 15-year-olds. It’s the first COVID-19 shot authorized for this younger population.

“I cannot tell you how many people have been anxiously awaiting this day to get their kids vaccinated,” says Dr. Flor Munoz, a pediatric infectious disease specialist at Texas Children’s Hospital and Baylor College of Medicine, and a member of the infectious disease committee of the American Academy of Pediatrics.

The green light was based on review of data the two companies released in March showing that two doses of their vaccine provided similar protection from COVID-19 disease among this age group as it did for adults. Among the more than 2,200 teens in the study group the FDA reviewed, 16 developed COVID-19—none of them were in the vaccinated group. The companies’ studies found that levels of virus-fighting antibodies … Read the rest

Tezepelumab BLA Submitted for Severe Asthma

May 11, 2021 0 Comments

The Biologics License Application (BLA) for tezepelumab has been submitted to the Food and Drug Administration (FDA) for patients with severe asthma.

Tezepelumab is an investigational first-in-class human monoclonal antibody that works by blocking thymic stromal lymphopoietin, an epithelial cytokine involved in the initiation and persistence of airway inflammation. 

The BLA submission is supported by data from the PATHFINDER clinical program, which included the double-blind, placebo-controlled phase 3 NAVIGATOR trial (ClinicalTrials.gov: NCT03347279) that assessed the efficacy and safety of tezepelumab in 1061 patients 12 to 80 years of age with severe, uncontrolled asthma who were receiving medium- or high-dose inhaled corticosteroid plus at least 1 additional controller medication with or without oral corticosteroid. The study included patients with both high and low blood eosinophil counts.

Patients were randomly assigned 1:1 to receive tezepelumab or placebo administered by subcutaneous injection, in addition to standard of care. The primary end point of … Read the rest

Genetically Modified Mosquitoes Have Come to the U.S. Will They Work?

May 10, 2021 0 Comments

“Our Mosquito Project Takes Flight,” reads a baby-blue billboard off US-1 in the Florida Keys, alongside an image of an insect tracing a path in the shape of a heart. Sponsored by the local mosquito control board and U.K.-based biotech firm Oxitec, the ad promotes a contentious plan to release millions of genetically modified Aedes aegypti mosquitoes here to test a new method of bioengineered pest control. It’s the first-ever such experiment in the United States, and one that has turned this chain of sun-soaked island communities into a battleground over scientific truth, government authority, and humanity’s right to modify nature. Even this bit of roadside signage is contested. Four months ago, the billboard carried a different ad, paid for by the Coalition Against GMO Mosquitoes, an organization with the mission of stopping releases of the genetically modified insects in the U.S., “WARNING!!!,” it read then, “GENETICALLY MODIFIED MOSQUITOES TO … Read the rest

Electronic Nicotine Delivery System May Reduce Toxicant Exposure, Cigarette Consumption

May 10, 2021 0 Comments

People using electronic nicotine delivery systems (ENDS) with cigarette-like nicotine delivery may reduce their exposure to a tobacco-specific carcinogen metabolite, even with concurrent smoking, according to study results published in The Lancet Respiratory Medicine.

Investigators conducted a 4-arm, parallel-group, randomized controlled study (ClinicalTrials.gov Identifier: NCT02342795) to determine how much ENDS or nonnicotine cigarette substitutes influence toxicant exposure related to tobacco and cigarette consumption in individuals who were interested in reducing their smoking frequency.

Adults aged 21 to 65 years who smoked more than 9 cigarettes a day for at least the past year, who wanted to reduce their smoking frequency, but not quit, were invited to be randomly assigned to receive either a cartomizer-based, pen-style ENDS with 0 mg/mL, 8 mg/mL, or 36 mg/mL liquid nicotine or a nonelectronic cigarette-shaped plastic tube that contained no nicotine or aerosol (cigarette substitute; unmasked) for 24 weeks.

The primary outcome measured the concentration … Read the rest

GlobalLink

May 9, 2021 0 Comments

Balsamic vinegar is related to only two potential well being issues. It could erode dental enamel because of its acidity, and it may contain some lead.

modern healthcare magazine

In as we speak’s world, technology performs an vital position in the advancement of the healthcare industry for saving numerous lives all around the globe. Few phrases produce a worry issue for women because the phrases “breast cancer”. The very best protection against breast cancer is information of the methods you may reduce the danger of buying this dreaded disease. All these well being and social problems are likely sciencefile to accumulate and intensify over time, finally lowering folks’s high quality of life, whereas creating multiple, advanced, costly care wants. In an inside survey conducted final 12 months by financial institution auditors, seventy seven {d88ec4a771b38d36e747acb18ed3240a91adf6c3faa273fad2adf67e1f235525} of employees accountable for imposing the establishment’s safeguards stated they suppose that administration does not worth” … Read the rest

WHO Panel Authorizes Emergency Use of China’s Sinopharm Vaccine

May 9, 2021 0 Comments

(GENEVA) — The World Health Organization gave emergency use authorization Friday to a COVID-19 vaccine manufactured by China’s Sinopharm, potentially paving the way for millions of the doses to reach needy countries through a U.N.-backed program rolling out coronavirus vaccines.

The decision by a WHO technical advisory group, a first for a Chinese vaccine, opens the possibility that Sinopharm’s offering could be included in the U.N.-backed COVAX program in coming weeks or months and distributed through U.N. children’s agency UNICEF and WHO’s Americas regional office.

Aside from efficacy numbers, the Chinese manufacturer has released very little public data about its two vaccines – one developed by its Beijing Institute of Biological Products and the other by the Wuhan Institute of Biological Products.

The Beijing shot is one the WHO advisory group considered for the emergency use listing.

“This afternoon, WHO gave emergency use listing to sign off on Beijing’s COVID-19 … Read the rest

Strategies for Managing Uncertainty in Patient Care

May 9, 2021 0 Comments

One of the central themes of physicians’ professional lives this past year has been the lack of certainty when addressing COVID-19. From a public health perspective, the knowledge base over the importance of face masking has changed and evolved while the risks and benefits of various formulations of COVID vaccines have shifted. From a patient care perspective, what constitutes an effective and safe therapeutic against SARS-CoV-2 has been less a certainty and more of an evolving science. Although these gaps in knowledge are expected in medicine, they feel more significant now and are probably likely to increase. The public has confronted the widespread uncertainty as well, and has had to struggle to learn how to adapt to the evolving knowledge base. 

Uncertainty, which is the conscious awareness of not fully knowing, is central to the experience of caring for patients.1 Diagnostic, prognostic and treatment processes in patient care are … Read the rest